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Dysregulated Retinoic Acid Signaling in the Pathogenesis of Pseudoexfoliation Syndrome

Pseudoexfoliation (PEX) syndrome, a stress-induced fibrotic matrix process, is the most common recognizable cause of open-angle glaucoma worldwide. The recent identification of PEX-associated gene variants uncovered the vitamin A metabolic pathway as a factor influencing the risk of disease. In this...

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Detalles Bibliográficos
Autores principales: Zenkel, Matthias, Hoja, Ursula, Gießl, Andreas, Berner, Daniel, Hohberger, Bettina, Weller, Julia M., König, Loretta, Hübner, Lisa, Ostermann, Thomas A., Gusek-Schneider, Gabriele C., Kruse, Friedrich E., Pasutto, Francesca, Schlötzer-Schrehardt, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180992/
https://www.ncbi.nlm.nih.gov/pubmed/35682657
http://dx.doi.org/10.3390/ijms23115977