Pathogenic Impact of α-Synuclein Phosphorylation and Its Kinases in α-Synucleinopathies

α-Synuclein is a protein with a molecular weight of 14.5 kDa and consists of 140 amino acids encoded by the SNCA gene. Missense mutations and gene duplications in the SNCA gene cause hereditary Parkinson’s disease. Highly phosphorylated and abnormally aggregated α-synuclein is a major component of L...

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Detalles Bibliográficos
Autores principales: Kawahata, Ichiro, Finkelstein, David I., Fukunaga, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181156/
https://www.ncbi.nlm.nih.gov/pubmed/35682892
http://dx.doi.org/10.3390/ijms23116216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181156/
https://www.ncbi.nlm.nih.gov/pubmed/35682892
http://dx.doi.org/10.3390/ijms23116216

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