On the origin of nitrosylated hemoglobin in COVID-19: Endothelial NO capture or redox conversion of nitrite?: Experimental results and a cautionary note on challenges in translational research

In blood, the majority of endothelial nitric oxide (NO) is scavenged by oxyhemoglobin, forming nitrate while a small part reacts with dissolved oxygen to nitrite; another fraction may bind to deoxyhemoglobin to generate nitrosylhemoglobin (HbNO) and/or react with a free cysteine to form a nitrosothi...

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Detalles Bibliográficos
Autores principales: Nogueira, Renato C., Minnion, Magdalena, Clark, Anna D., Dyson, Alex, Tanus-Santos, José E., Feelisch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181201/
https://www.ncbi.nlm.nih.gov/pubmed/35709537
http://dx.doi.org/10.1016/j.redox.2022.102362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181201/
https://www.ncbi.nlm.nih.gov/pubmed/35709537
http://dx.doi.org/10.1016/j.redox.2022.102362

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