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A Novel Synthetic Antibody Library with Complementarity-Determining Region Diversities Designed for an Improved Amplification Profile

Antibody discovery by phage display consists of two phases, i.e., the binding phase and the amplification phase. Ideally, the selection process is dominated by the former, and all the retrieved clones are amplified equally during the latter. In reality, the amplification efficiency of antibody fragm...

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Detalles Bibliográficos
Autores principales: Bai, Xuelian, Jang, Moonseon, Lee, Nam Ju, Nguyen, Thi Thu Ha, Jung, Mooyoung, Hwang, Jeong Yeon, Shim, Hyunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181208/
https://www.ncbi.nlm.nih.gov/pubmed/35682935
http://dx.doi.org/10.3390/ijms23116255