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The Disordered EZH2 Loop: Atomic Level Characterization by (1)H(N)- and (1)H(α)-Detected NMR Approaches, Interaction with the Long Noncoding HOTAIR RNA
The 96-residue-long loop of EZH2 is proposed to play a role in the interaction with long non-coding RNAs (lncRNAs) and to contribute to EZH2 recruitment to the chromatin. However, molecular details of RNA recognition have not been described so far. Cellular studies have suggested that phosphorylatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181245/ https://www.ncbi.nlm.nih.gov/pubmed/35682829 http://dx.doi.org/10.3390/ijms23116150 |