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A diminished immune response underlies age-related SARS-CoV-2 pathologies

Morbidity and mortality in response to SARS-CoV-2 infection are significantly elevated in people of advanced age. To understand the underlying biology of this phenotype, we utilize the golden hamster model to compare how the innate and adaptive immune responses to SARS-CoV-2 infection differed betwe...

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Detalles Bibliográficos
Autores principales: Oishi, Kohei, Horiuchi, Shu, Frere, Justin, Schwartz, Robert E., tenOever, Benjamin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181267/
https://www.ncbi.nlm.nih.gov/pubmed/35714615
http://dx.doi.org/10.1016/j.celrep.2022.111002