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LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages

Reprogramming of metabolic pathways in monocytes and macrophages can induce a proatherosclerotic inflammatory memory called trained innate immunity. Here, we have analyzed the role of the Liver X receptor (LXR), a crucial regulator of metabolism and inflammation, in oxidized low-density lipoprotein...

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Detalles Bibliográficos
Autores principales: Findeisen, Hannes M., Voges, Vivienne C., Braun, Laura C., Sonnenberg, Jannik, Schwarz, Dennis, Körner, Helena, Reinecke, Holger, Sohrabi, Yahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181299/
https://www.ncbi.nlm.nih.gov/pubmed/35682840
http://dx.doi.org/10.3390/ijms23116166