Cargando…

LXRα Regulates oxLDL-Induced Trained Immunity in Macrophages

Reprogramming of metabolic pathways in monocytes and macrophages can induce a proatherosclerotic inflammatory memory called trained innate immunity. Here, we have analyzed the role of the Liver X receptor (LXR), a crucial regulator of metabolism and inflammation, in oxidized low-density lipoprotein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Findeisen, Hannes M., Voges, Vivienne C., Braun, Laura C., Sonnenberg, Jannik, Schwarz, Dennis, Körner, Helena, Reinecke, Holger, Sohrabi, Yahya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181299/ https://www.ncbi.nlm.nih.gov/pubmed/35682840 http://dx.doi.org/10.3390/ijms23116166

Ejemplares similares

Mechanisms of Trained Innate Immunity in oxLDL Primed Human Coronary Smooth Muscle Cells
por: Schnack, Lucia, et al.
Publicado: (2019)

mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes
por: Sohrabi, Yahya, et al.
Publicado: (2019)

Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL
por: Kimmel, Danielle W., et al.
Publicado: (2017)

LOX-1, OxLDL, and Atherosclerosis
por: Pirillo, Angela, et al.
Publicado: (2013)

oxLDL and eLDL Induced Membrane Microdomains in Human Macrophages
por: Wallner, Stefan, et al.
Publicado: (2016)

The association between serum levels of oxLDL-lgG and oxLDL-lgM autoantibody with adult acute myeloblastic leukaemia
por: Li, Hao, et al.
Publicado: (2010)

Impact of oxLDL on Cholesterol-Rich Membrane Rafts
por: Levitan, Irena, et al.
Publicado: (2011)

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy
por: Gutwein, Paul, et al.
Publicado: (2009)

OxLDL as an Inducer of a Metabolic Shift in Cancer Cells
por: Bitorina, Albert V., et al.
Publicado: (2021)

Data on autophagy markers in human macrophages exposed to oxLDL and growth differentiation factor-15
por: Ackermann, Kathrin, et al.
Publicado: (2019)

oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming
por: Groh, Laszlo A., et al.
Publicado: (2021)

Early Transcriptomic Response to LDL and oxLDL in Human Vascular Smooth Muscle Cells
por: Damián-Zamacona, Salvador, et al.
Publicado: (2016)

Dyslipidemia-Induced Neuropathy in Mice: The Role of oxLDL/LOX-1
por: Vincent, Andrea M., et al.
Publicado: (2009)

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2021)

Immune modulatory effects of progesterone on oxLDL‐induced trained immunity in monocytes
por: Groh, Laszlo A., et al.
Publicado: (2022)

Niacin Reverses Migratory Macrophage Foam Cell Arrest Mediated by oxLDL In Vitro
por: Huang, Hua, et al.
Publicado: (2014)

Simvastatin promotes NPC1‐mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL‐loaded macrophages
por: Xu, Xiaoyang, et al.
Publicado: (2016)

Systems Approach to Study Associations between OxLDL and Abdominal Aortic Aneurysms
por: Gutowski, Łukasz, et al.
Publicado: (2019)

Early Transcriptomic Response to OxLDL in Human Retinal Pigment Epithelial Cells
por: Koirala, Diwa, et al.
Publicado: (2020)

Astragaloside IV Reduces OxLDL-Induced BNP Overexpression by Regulating HDAC
por: Zhang, Wenting, et al.
Publicado: (2021)

Exposure to oxLDL impairs TGF-β activity in human tendon cells
por: Mousavizadeh, Rouhollah, et al.
Publicado: (2023)

Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice
por: Talbot, Maude, et al.
Publicado: (2018)

Co-Stimulation of PAFR and CD36 Is Required for oxLDL-Induced Human Macrophages Activation
por: Rios, Francisco J. O., et al.
Publicado: (2012)

GDF-15 Suppresses Atherosclerosis by Inhibiting oxLDL-Induced Lipid Accumulation and Inflammation in Macrophages
por: Huang, Hong, et al.
Publicado: (2021)

Passive Immunization with Hypochlorite-oxLDL Specific Antibodies Reduces Plaque Volume in LDL Receptor-Deficient Mice
por: van Leeuwen, Marcella, et al.
Publicado: (2013)

Ethyl pyruvate inhibits oxidation of LDL in vitro and attenuates oxLDL toxicity in EA.hy926 cells
por: Rossmann, Christine, et al.
Publicado: (2018)

oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21
por: Nickel, Thomas, et al.
Publicado: (2012)

Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction
por: Vrieling, Frank, et al.
Publicado: (2019)

Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity
por: Zheng, Tony J., et al.
Publicado: (2022)

Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage
por: Zhang, Heng, et al.
Publicado: (2015)

c-Ski Inhibits Autophagy of Vascular Smooth Muscle Cells Induced by oxLDL and PDGF
por: Li, Jun, et al.
Publicado: (2014)

Circulating CD36 and oxLDL levels are associated with cardiovascular risk factors in young subjects
por: Ramos-Arellano, Luz E, et al.
Publicado: (2014)

Calpain-1 Mediated Disorder of Pyrophosphate Metabolism Contributes to Vascular Calcification Induced by oxLDL
por: Tang, Futian, et al.
Publicado: (2015)

Pinoresinol Diglucoside Alleviates oxLDL-Induced Dysfunction in Human Umbilical Vein Endothelial Cells
por: Yao, Jinpeng, et al.
Publicado: (2016)

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha
por: Tsai, Kun-Ling, et al.
Publicado: (2016)

oxLDL promotes podocyte migration by regulating CXCL16, ADAM10 and ACTN4
por: Chen, Yuan, et al.
Publicado: (2020)

Mettl3 promotes oxLDL‐mediated inflammation through activating STAT1 signaling
por: Li, Zhenwei, et al.
Publicado: (2021)

Pulse Wave Velocity Is Associated with Increased Plasma oxLDL in Ageing but Not with FGF21 and Habitual Exercise
por: Lee, Shuen Yee, et al.
Publicado: (2020)

β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages
por: Lee, Tzong-Shyuan, et al.
Publicado: (2015)

Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages
por: Varì, Rosaria, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_lr11dqqga8u090g1taaopi46gd