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Vitamin B6 Deficiency Promotes Loss of Heterozygosity (LOH) at the Drosophila warts (wts) Locus

The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), is a cofactor for more than 200 enzymes involved in many metabolic pathways. Moreover, PLP has antioxidant properties and quenches the reactive oxygen species (ROS). Accordingly, PLP deficiency causes chromosome aberrations in Drosophila,...

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Detalles Bibliográficos
Autores principales: Gnocchini, Eleonora, Pilesi, Eleonora, Schiano, Ludovica, Vernì, Fiammetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181336/
https://www.ncbi.nlm.nih.gov/pubmed/35682766
http://dx.doi.org/10.3390/ijms23116087