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Vitamin B6 Deficiency Promotes Loss of Heterozygosity (LOH) at the Drosophila warts (wts) Locus
The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), is a cofactor for more than 200 enzymes involved in many metabolic pathways. Moreover, PLP has antioxidant properties and quenches the reactive oxygen species (ROS). Accordingly, PLP deficiency causes chromosome aberrations in Drosophila,...
Autores principales: | Gnocchini, Eleonora, Pilesi, Eleonora, Schiano, Ludovica, Vernì, Fiammetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181336/ https://www.ncbi.nlm.nih.gov/pubmed/35682766 http://dx.doi.org/10.3390/ijms23116087 |
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