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Ovulation Enhances Intraperitoneal and Ovarian Seedings of High-Grade Serous Carcinoma Cells Originating from the Fallopian Tube: Confirmation in a Bursa-Free Mouse Xenograft Model

Background: Recently, new paradigms for the etiology and origin of ovarian high-grade serous carcinoma (HGSC) have emerged. The carcinogens released during ovulation transform fallopian tube epithelial cells, exfoliating and metastasizing to the peritoneal organs, including the ovaries. Solid in viv...

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Detalles Bibliográficos
Autores principales: Hsu, Che-Fang, Seenan, Vaishnavi, Wang, Liang-Yuan, Chu, Tang-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181345/
https://www.ncbi.nlm.nih.gov/pubmed/35682896
http://dx.doi.org/10.3390/ijms23116211