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Mitochondrial rRNA Methylation by Mettl15 Contributes to the Exercise and Learning Capability in Mice

Mitochondrial translation is a unique relic of the symbiotic origin of the organelle. Alterations of its components cause a number of severe human diseases. Hereby we report a study of mice devoid of Mettl15 mitochondrial 12S rRNA methyltransferase, responsible for the formation of m(4)C839 residue...

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Detalles Bibliográficos
Autores principales: Averina, Olga A., Laptev, Ivan G., Emelianova, Mariia A., Permyakov, Oleg A., Mariasina, Sofia S., Nikiforova, Alyona I., Manskikh, Vasily N., Grigorieva, Olga O., Bolikhova, Anastasia K., Kalabin, Gennady A., Dontsova, Olga A., Sergiev, Petr V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181494/
https://www.ncbi.nlm.nih.gov/pubmed/35682734
http://dx.doi.org/10.3390/ijms23116056