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Lysosomal Exocytosis of Olivacine on the Way to Explain Drug Resistance in Cancer Cells
Ellipticine is an indole alkaloid with proven antitumor activity against various tumors in vitro and a diverse mechanism of action, which includes topoisomerase II inhibition, intercalation, and cell cycle impact. Olivacine—ellipticine’s isomer—shows similar properties. The objectives of this work w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181543/ https://www.ncbi.nlm.nih.gov/pubmed/35682799 http://dx.doi.org/10.3390/ijms23116119 |