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The Role of Autophagy and Pyroptosis in Liver Disorders

Pyroptosis is a programmed cell death caused by inflammasomes, which can detect cell cytosolic contamination or disturbance. In pyroptosis, caspase-1 or caspase-11/4/5 is activated, cleaving gasdermin D to separate its N-terminal pore-forming domain (PFD). The oligomerization of PFD forms macropores...

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Detalles Bibliográficos
Autores principales: Zhao, Huijie, Liu, Huiyang, Yang, Yihan, Wang, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181643/
https://www.ncbi.nlm.nih.gov/pubmed/35682887
http://dx.doi.org/10.3390/ijms23116208