Allosteric Binding Sites of Aβ Peptides on the Acetylcholine Synthesizing Enzyme ChAT as Deduced by In Silico Molecular Modeling

The native function of amyloid-β (Aβ) peptides is still unexplored. However, several recent reports suggest a prominent role of Aβ peptides in acetylcholine homeostasis. To clarify this role of Aβ, we have reported that Aβ peptides at physiological concentrations can directly enhance the catalytic e...

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Detalles Bibliográficos
Autores principales: Baidya, Anurag TK, Kumar, Amit, Kumar, Rajnish, Darreh-Shori, Taher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181666/
https://www.ncbi.nlm.nih.gov/pubmed/35682752
http://dx.doi.org/10.3390/ijms23116073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181666/
https://www.ncbi.nlm.nih.gov/pubmed/35682752
http://dx.doi.org/10.3390/ijms23116073

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