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Allosteric Binding Sites of Aβ Peptides on the Acetylcholine Synthesizing Enzyme ChAT as Deduced by In Silico Molecular Modeling
The native function of amyloid-β (Aβ) peptides is still unexplored. However, several recent reports suggest a prominent role of Aβ peptides in acetylcholine homeostasis. To clarify this role of Aβ, we have reported that Aβ peptides at physiological concentrations can directly enhance the catalytic e...
Autores principales: | Baidya, Anurag TK, Kumar, Amit, Kumar, Rajnish, Darreh-Shori, Taher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181666/ https://www.ncbi.nlm.nih.gov/pubmed/35682752 http://dx.doi.org/10.3390/ijms23116073 |
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