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A New Perspective on Huntington’s Disease: How a Neurological Disorder Influences the Peripheral Tissues

Huntington’s disease (HD) is a neurodegenerative disorder caused by a toxic, aggregation-prone expansion of CAG repeats in the HTT gene with an age-dependent progression that leads to behavioral, cognitive and motor symptoms. Principally affecting the frontal cortex and the striatum, mHTT disrupts m...

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Detalles Bibliográficos
Autores principales: Gómez-Jaramillo, Laura, Cano-Cano, Fátima, González-Montelongo, María del Carmen, Campos-Caro, Antonio, Aguilar-Diosdado, Manuel, Arroba, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181740/
https://www.ncbi.nlm.nih.gov/pubmed/35682773
http://dx.doi.org/10.3390/ijms23116089