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Biochemical, Structural Analysis, and Docking Studies of Spiropyrazoline Derivatives

In this study, we evaluated the antiproliferative potential, DNA damage, crystal structures, and docking calculation of two spiropyrazoline derivatives. The main focus of the research was to evaluate the antiproliferative potential of synthesized compounds towards eight cancer cell lines. Compound I...

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Detalles Bibliográficos
Autores principales: Adamus-Grabicka, Angelika A., Daśko, Mateusz, Hikisz, Pawel, Kusz, Joachim, Malecka, Magdalena, Budzisz, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181777/
https://www.ncbi.nlm.nih.gov/pubmed/35682740
http://dx.doi.org/10.3390/ijms23116061