Cu(I)/Pd(II)-Catalyzed Intramolecular Hydroamidation and C-H Dehydrogenative Coupling of ortho-Alkynyl-N-arylbenzamides for Access to Isoindolo[2,1-a]Indol-6-Ones

An efficient, atom-economic and one-pot synthesis of isoindolo[2,1-a]indol-6-ones via CuI/Pd(OAc)(2)-catalyzed intramolecular hydroamidation of alkynyl group, and C-H dehydrogenative coupling of ortho-alkynyl-N-arylbenzamides has been developed. This transformation occurs with the use of oxygen as t...

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Detalles Bibliográficos
Autores principales: Tang, Baoxin, Hua, Ruimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181885/
https://www.ncbi.nlm.nih.gov/pubmed/35684329
http://dx.doi.org/10.3390/molecules27113393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181885/
https://www.ncbi.nlm.nih.gov/pubmed/35684329
http://dx.doi.org/10.3390/molecules27113393

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