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Fluorinated Analogues of Lepidilines A and C: Synthesis and Screening of Their Anticancer and Antiviral Activity

Starting with fluorinated benzylamines, a series of 2-unsubstituted imidazole N-oxides was prepared and subsequently deoxygenated in order to prepare the corresponding imidazoles. The latter were treated with benzyl halides yielding imidazolium salts, which are considered fluorinated analogues of na...

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Detalles Bibliográficos
Autores principales: Mlostoń, Grzegorz, Kowalczyk, Mateusz, Celeda, Małgorzata, Jasiński, Marcin, Denel-Bobrowska, Marta, Olejniczak, Agnieszka B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181938/
https://www.ncbi.nlm.nih.gov/pubmed/35684460
http://dx.doi.org/10.3390/molecules27113524