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Solid-Phase Synthesized Copolymers for the Assembly of pH-Sensitive Micelles Suitable for Drug Delivery Applications

Diblock copolymers of polyhistidine are known for their self-assembly into micelles and their pH-dependent disassembly due to the amphiphilic character of the copolymer and the unsaturated imidazole groups that undergo a hydrophobic-to-hydrophilic transition in an acidic pH. This property has been l...

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Detalles Bibliográficos
Autores principales: Ghiarasim, Razvan, Tiron, Crina Elena, Tiron, Adrian, Dimofte, Mihail-Gabriel, Pinteala, Mariana, Rotaru, Alexandru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9181997/
https://www.ncbi.nlm.nih.gov/pubmed/35683654
http://dx.doi.org/10.3390/nano12111798