Identification of New Non-BBB Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty Liver Disease

Serotonin (5-hydroxytryptophan) is a hormone that regulates emotions in the central nervous system. However, serotonin in the peripheral system is associated with obesity and fatty liver disease. Because serotonin cannot cross the blood-brain barrier (BBB), we focused on identifying new tryptophan h...

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Detalles Bibliográficos
Autores principales: Pagire, Suvarna H., Pagire, Haushabhau S., Park, Kun-Young, Bae, Eun Jung, Kim, Kwang-eun, Kim, Minhee, Yoon, Jihyeon, Parameswaran, Saravanan, Choi, Jun-Ho, Park, Sungmi, Jeon, Jae-Han, Song, Jin Sook, Bae, Myung Ae, Lee, In-Kyu, Kim, Hail, Suh, Jae Myoung, Ahn, Jin Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182086/
https://www.ncbi.nlm.nih.gov/pubmed/35684355
http://dx.doi.org/10.3390/molecules27113417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182086/
https://www.ncbi.nlm.nih.gov/pubmed/35684355
http://dx.doi.org/10.3390/molecules27113417

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