Cholesterol Dependent Activity of the Adenosine A(2A) Receptor Is Modulated via the Cholesterol Consensus Motif

Background: Membrane cholesterol dysregulation has been shown to alter the activity of the adenosine A(2A) receptor (A(2A)R), a G protein-coupled receptor, thereby implicating cholesterol levels in diseases such as Alzheimer’s and Parkinson’s. A limited number of A(2A)R crystal structures show the r...

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Detalles Bibliográficos
Autores principales: McGraw, Claire, Koretz, Kirsten Swonger, Oseid, Daniel, Lyman, Edward, Robinson, Anne Skaja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182133/
https://www.ncbi.nlm.nih.gov/pubmed/35684466
http://dx.doi.org/10.3390/molecules27113529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182133/
https://www.ncbi.nlm.nih.gov/pubmed/35684466
http://dx.doi.org/10.3390/molecules27113529

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