Assay Development and Identification of the First Plasmodium falciparum 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Inhibitors

In the fight towards eradication of malaria, identifying compounds active against new drug targets constitutes a key approach. Plasmodium falciparum 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (PfHPPK) has been advanced as a promising target, as being part of the parasite essential folate bi...

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Detalles Bibliográficos
Autores principales: Hoarau, Marie, Suwanakitti, Nattida, Varatthan, Thaveechai, Thiabma, Ratthiya, Rattanajak, Roonglawan, Charoensetakul, Netnapa, Redman, Emily K., Khotavivattana, Tanatorn, Vilaivan, Tirayut, Yuthavong, Yongyuth, Kamchonwongpaisan, Sumalee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182141/
https://www.ncbi.nlm.nih.gov/pubmed/35684452
http://dx.doi.org/10.3390/molecules27113515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182141/
https://www.ncbi.nlm.nih.gov/pubmed/35684452
http://dx.doi.org/10.3390/molecules27113515

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