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Assay Development and Identification of the First Plasmodium falciparum 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Inhibitors

In the fight towards eradication of malaria, identifying compounds active against new drug targets constitutes a key approach. Plasmodium falciparum 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (PfHPPK) has been advanced as a promising target, as being part of the parasite essential folate bi...

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Detalles Bibliográficos
Autores principales:	Hoarau, Marie, Suwanakitti, Nattida, Varatthan, Thaveechai, Thiabma, Ratthiya, Rattanajak, Roonglawan, Charoensetakul, Netnapa, Redman, Emily K., Khotavivattana, Tanatorn, Vilaivan, Tirayut, Yuthavong, Yongyuth, Kamchonwongpaisan, Sumalee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182141/ https://www.ncbi.nlm.nih.gov/pubmed/35684452 http://dx.doi.org/10.3390/molecules27113515

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