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BSA Interaction, Molecular Docking, and Antibacterial Activity of Zinc(II) Complexes Containing the Sterically Demanding Biomimetic N(3)S(2) Ligand: The Effect of Structure Flexibility

Two zinc(II) complexes, DBZ and DBZH(4), that have (ZnN(3)S(2)) cores and differ in the bridging mode of the ligating backbone, effectively bind to BSA. The binding affinity varies as DBZ > DBZH(4) and depends on the ligand structure. At low concentrations, both complexes exhibit dynamic quenchin...

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Detalles Bibliográficos
Autores principales: Soliman, Eman, Ibrahim, Mohamed M., El-Khouly, Mohamed E., El-Mehasseb, Ibrahim, Ramadan, Abd El-Motaleb M., Mahfouz, Magdy E., Shaban, Shaban Y., van Eldik, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182146/
https://www.ncbi.nlm.nih.gov/pubmed/35684479
http://dx.doi.org/10.3390/molecules27113543