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BSA Interaction, Molecular Docking, and Antibacterial Activity of Zinc(II) Complexes Containing the Sterically Demanding Biomimetic N(3)S(2) Ligand: The Effect of Structure Flexibility
Two zinc(II) complexes, DBZ and DBZH(4), that have (ZnN(3)S(2)) cores and differ in the bridging mode of the ligating backbone, effectively bind to BSA. The binding affinity varies as DBZ > DBZH(4) and depends on the ligand structure. At low concentrations, both complexes exhibit dynamic quenchin...
Autores principales: | Soliman, Eman, Ibrahim, Mohamed M., El-Khouly, Mohamed E., El-Mehasseb, Ibrahim, Ramadan, Abd El-Motaleb M., Mahfouz, Magdy E., Shaban, Shaban Y., van Eldik, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182146/ https://www.ncbi.nlm.nih.gov/pubmed/35684479 http://dx.doi.org/10.3390/molecules27113543 |
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