Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model

Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells’ proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their clinical value. One TKI that has been developed recently but not explored much is...

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Detalles Bibliográficos
Autores principales: Al-Thani, Hissa F., Shurbaji, Samar, Zakaria, Zain Zaki, Hasan, Maram H., Goracinova, Katerina, Korashy, Hesham M., Yalcin, Huseyin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182153/
https://www.ncbi.nlm.nih.gov/pubmed/35683259
http://dx.doi.org/10.3390/ma15113960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182153/
https://www.ncbi.nlm.nih.gov/pubmed/35683259
http://dx.doi.org/10.3390/ma15113960

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