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Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model
Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells’ proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their clinical value. One TKI that has been developed recently but not explored much is...
Autores principales: | Al-Thani, Hissa F., Shurbaji, Samar, Zakaria, Zain Zaki, Hasan, Maram H., Goracinova, Katerina, Korashy, Hesham M., Yalcin, Huseyin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182153/ https://www.ncbi.nlm.nih.gov/pubmed/35683259 http://dx.doi.org/10.3390/ma15113960 |
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