Borylated 2,3,4,5-Tetrachlorophthalimide and Their 2,3,4,5-Tetrachlorobenzamide Analogues: Synthesis, Their Glycosidase Inhibition and Anticancer Properties in View to Boron Neutron Capture Therapy

Tetrachlorinated phthalimide analogues bearing a boron-pinacolate ester group were synthesised via two synthetic routes and evaluated in their glycosidase modulating and anticancer properties, with a view to use them in boron neutron capture therapy (BNCT), a promising radiation type for cancer, as...

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Detalles Bibliográficos
Autores principales: Campkin, David M., Shimadate, Yuna, Bartholomew, Barbara, Bernhardt, Paul V., Nash, Robert J., Sakoff, Jennette A., Kato, Atsushi, Simone, Michela I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182199/
https://www.ncbi.nlm.nih.gov/pubmed/35684388
http://dx.doi.org/10.3390/molecules27113447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182199/
https://www.ncbi.nlm.nih.gov/pubmed/35684388
http://dx.doi.org/10.3390/molecules27113447

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