Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations

Acetylcholinesterase (AChE) inhibitors and calcium channel blockers are considered effective therapies for Alzheimer’s disease. AChE plays an essential role in the nervous system by catalyzing the hydrolysis of the neurotransmitter acetylcholine. In this study, the inhibition of the enzyme AChE by S...

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Detalles Bibliográficos
Autores principales: Khalid, Asaad, Abdalla, Mohnad, Saeed, Maria, Ghayur, Muhammad Nabeel, Kalauni, Surya Kant, Albratty, Mohammed, Alhazmi, Hassan A., Mesaik, Mohammed Ahmed, Gilani, Anwarul Hassan, Ul-Haq, Zaheer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182202/
https://www.ncbi.nlm.nih.gov/pubmed/35684298
http://dx.doi.org/10.3390/molecules27113361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182202/
https://www.ncbi.nlm.nih.gov/pubmed/35684298
http://dx.doi.org/10.3390/molecules27113361

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