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Effect of Solvents on Proline Modified at the Secondary Sphere: A Multivariate Exploration
[Image: see text] The critical influence of solvent effects on proline-catalyzed aldol reactions has been extensively described. Herein, we apply multivariate regression strategies to probe the influence of different solvents on an aldol reaction catalyzed by proline modified at its secondary sphere...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182215/ https://www.ncbi.nlm.nih.gov/pubmed/35019660 http://dx.doi.org/10.1021/acs.joc.1c02778 |