Antiviral Activity of a Cyclic Pro-Pro-β(3)-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5

The core of Cyclolinopeptide A (CLA, cyclo(LIILVPPFF)), responsible for its high immunosuppressive activity, contains a Pro-Pro-Phe-Phe sequence. A newly synthesized cyclic tetrapeptide, cyclo(Pro-Pro-β(3)-HoPhe-Phe) (denoted as 4B8M) bearing the active sequence of CLA, was recently shown to exhibit...

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Detalles Bibliográficos
Autores principales: Zaczyńska, Ewa, Kaczmarek, Krzysztof, Zabrocki, Janusz, Artym, Jolanta, Zimecki, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182219/
https://www.ncbi.nlm.nih.gov/pubmed/35684487
http://dx.doi.org/10.3390/molecules27113552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182219/
https://www.ncbi.nlm.nih.gov/pubmed/35684487
http://dx.doi.org/10.3390/molecules27113552

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