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Antiviral Activity of a Cyclic Pro-Pro-β(3)-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5
The core of Cyclolinopeptide A (CLA, cyclo(LIILVPPFF)), responsible for its high immunosuppressive activity, contains a Pro-Pro-Phe-Phe sequence. A newly synthesized cyclic tetrapeptide, cyclo(Pro-Pro-β(3)-HoPhe-Phe) (denoted as 4B8M) bearing the active sequence of CLA, was recently shown to exhibit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182219/ https://www.ncbi.nlm.nih.gov/pubmed/35684487 http://dx.doi.org/10.3390/molecules27113552 |