Age and sex effects on DNA methylation sites linked to genes implicated in severe COVID-19 and SARS-CoV-2 host cell entry

Male sex and advanced age are associated with severe symptoms of COVID-19. Sex and age also exhibit substantial associations with genome-wide DNA methylation (DNAm) differences in humans. Using a random sample of Illumina EPIC-based genome-wide methylomes from peripheral whole blood of 1,976 parents...

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Detalles Bibliográficos
Autores principales: Bohlin, Jon, Page, Christian M., Lee, Yunsung, Pettersson, John H.-O., Jugessur, Astanand, Magnus, Per, Håberg, Siri E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182232/
https://www.ncbi.nlm.nih.gov/pubmed/35679253
http://dx.doi.org/10.1371/journal.pone.0269105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182232/
https://www.ncbi.nlm.nih.gov/pubmed/35679253
http://dx.doi.org/10.1371/journal.pone.0269105

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