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A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge

BACKGROUND: Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23–90%) and recent emergence in West Africa for the first time. Although a recombinant vesicular stomatitis virus (rVSV)-based vaccine (Ervebo) is...

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Detalles Bibliográficos
Autores principales: Woolsey, Courtney, Cross, Robert W., Agans, Krystle N., Borisevich, Viktoriya, Deer, Daniel J., Geisbert, Joan B., Gerardi, Cheryl, Latham, Theresa E., Fenton, Karla A., Egan, Michael A., Eldridge, John H., Geisbert, Thomas W., Matassov, Demetrius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182267/
https://www.ncbi.nlm.nih.gov/pubmed/35622847
http://dx.doi.org/10.1371/journal.pntd.0010433