One-Step, Low-Cost, Operator-Friendly, and Scalable Procedure to Synthetize Highly Pure N-(4-ethoxyphenyl)-retinamide in Quantitative Yield without Purification Work-Up

It is widely reported that N-(4-hydroxyphenyl)-retinamide or fenretinide (4-HPR), which is a synthetic amide of all-trans-retinoic acid (ATRA), inhibits in vitro several types of tumors, including cancer cell lines resistant to ATRA, at 1–10 µM concentrations. Additionally, studies in rats and mice...

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Detalles Bibliográficos
Autores principales: Alfei, Silvana, Zuccari, Guendalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182364/
https://www.ncbi.nlm.nih.gov/pubmed/35684568
http://dx.doi.org/10.3390/molecules27113632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182364/
https://www.ncbi.nlm.nih.gov/pubmed/35684568
http://dx.doi.org/10.3390/molecules27113632

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