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The RHIM of the Immune Adaptor Protein TRIF Forms Hybrid Amyloids with Other Necroptosis-Associated Proteins

TIR-domain-containing adapter-inducing interferon-β (TRIF) is an innate immune protein that serves as an adaptor for multiple cellular signalling outcomes in the context of infection. TRIF is activated via ligation of Toll-like receptors 3 and 4. One outcome of TRIF-directed signalling is the activa...

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Detalles Bibliográficos
Autores principales: Baker, Max O. D. G., Shanmugam, Nirukshan, Pham, Chi L. L., Ball, Sarah R., Sierecki, Emma, Gambin, Yann, Steain, Megan, Sunde, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182532/
https://www.ncbi.nlm.nih.gov/pubmed/35684320
http://dx.doi.org/10.3390/molecules27113382