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Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction—Applications as Antiproliferative Agents

A study on the reactivity of 3-amino α,β-unsaturated γ-lactam derivatives obtained from a multicomponent reaction is presented. Key features of the substrates are the presence of an endocyclic α,β-unsaturated amide moiety and an enamine functionality. Following different synthetic protocols, the fun...

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Detalles Bibliográficos
Autores principales: López-Francés, Adrián, del Corte, Xabier, Serna-Burgos, Zuriñe, Martínez de Marigorta, Edorta, Palacios, Francisco, Vicario, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182551/
https://www.ncbi.nlm.nih.gov/pubmed/35684563
http://dx.doi.org/10.3390/molecules27113624