Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain

Sigma receptors modulate nociception, offering a potential therapeutic target to treat pain, but relatively little is known regarding the role of sigma-2 receptors (S2R) in nociception. The purpose of this study was to investigate the in vivo analgesic and anti-allodynic activity and liabilities of...

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Detalles Bibliográficos
Autores principales: Wilson, Lisa L., Alleyne, Amy R., Eans, Shainnel O., Cirino, Thomas J., Stacy, Heather M., Mottinelli, Marco, Intagliata, Sebastiano, McCurdy, Christopher R., McLaughlin, Jay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182558/
https://www.ncbi.nlm.nih.gov/pubmed/35684553
http://dx.doi.org/10.3390/molecules27113617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182558/
https://www.ncbi.nlm.nih.gov/pubmed/35684553
http://dx.doi.org/10.3390/molecules27113617

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