The Salmonella transmembrane effector SteD hijacks AP1-mediated vesicular trafficking for delivery to antigen-loading MHCII compartments

SteD is a transmembrane effector of the Salmonella SPI-2 type III secretion system that inhibits T cell activation by reducing the amounts of at least three proteins –major histocompatibility complex II (MHCII), CD86 and CD97 –from the surface of antigen-presenting cells. SteD specifically localises...

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Detalles Bibliográficos
Autores principales: Godlee, Camilla, Cerny, Ondrej, Liu, Mei, Blundell, Samkeliso, Gallagher, Alanna E., Shahin, Meriam, Holden, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182567/
https://www.ncbi.nlm.nih.gov/pubmed/35622870
http://dx.doi.org/10.1371/journal.ppat.1010252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182567/
https://www.ncbi.nlm.nih.gov/pubmed/35622870
http://dx.doi.org/10.1371/journal.ppat.1010252

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