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The Salmonella transmembrane effector SteD hijacks AP1-mediated vesicular trafficking for delivery to antigen-loading MHCII compartments
SteD is a transmembrane effector of the Salmonella SPI-2 type III secretion system that inhibits T cell activation by reducing the amounts of at least three proteins –major histocompatibility complex II (MHCII), CD86 and CD97 –from the surface of antigen-presenting cells. SteD specifically localises...
Autores principales: | Godlee, Camilla, Cerny, Ondrej, Liu, Mei, Blundell, Samkeliso, Gallagher, Alanna E., Shahin, Meriam, Holden, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182567/ https://www.ncbi.nlm.nih.gov/pubmed/35622870 http://dx.doi.org/10.1371/journal.ppat.1010252 |
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