HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages

Macrophages (MΦ) are increasingly recognized as HIV-1 target cells involved in the pathogenesis and persistence of infection. Paradoxically, in vitro infection assays suggest that virus isolates are mostly T-cell-tropic and rarely MΦ-tropic. The latter are assumed to emerge under CD4+ T-cell paucity...

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Detalles Bibliográficos
Autores principales: Han, Mingyu, Cantaloube-Ferrieu, Vincent, Xie, Maorong, Armani-Tourret, Marie, Woottum, Marie, Pagès, Jean-Christophe, Colin, Philippe, Lagane, Bernard, Benichou, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182568/
https://www.ncbi.nlm.nih.gov/pubmed/35622876
http://dx.doi.org/10.1371/journal.ppat.1010335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182568/
https://www.ncbi.nlm.nih.gov/pubmed/35622876
http://dx.doi.org/10.1371/journal.ppat.1010335

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