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HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages
Macrophages (MΦ) are increasingly recognized as HIV-1 target cells involved in the pathogenesis and persistence of infection. Paradoxically, in vitro infection assays suggest that virus isolates are mostly T-cell-tropic and rarely MΦ-tropic. The latter are assumed to emerge under CD4+ T-cell paucity...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182568/ https://www.ncbi.nlm.nih.gov/pubmed/35622876 http://dx.doi.org/10.1371/journal.ppat.1010335 |