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A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure

Children with obesity typically have larger left ventricular heart dimensions during adulthood. However, whether this is due to a persistent effect of adiposity extending into adulthood is challenging to disentangle due to confounding factors throughout the lifecourse. We conducted a multivariable m...

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Detalles Bibliográficos
Autores principales: O’Nunain, Katie, Park, Chloe, Urquijo, Helena, Leyden, Genevieve M., Hughes, Alun D., Davey Smith, George, Richardson, Tom G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182693/
https://www.ncbi.nlm.nih.gov/pubmed/35679339
http://dx.doi.org/10.1371/journal.pbio.3001656