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Construction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization and In vivo clinical comparative pharmacokinetic study in healthy human subjects

BACKGROUND: Disturbed sleep can cause to m health problems such as cognitive impairment, depressed mood, and negative effects on cardiovascular, endocrine, and immune function. This study formulates and optimizes Eszopiclone trilaminate fast dissolving film. METHODS: Prepared Eszopiclone trilaminate...

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Detalles Bibliográficos
Autores principales: Teaima, Mahmoud, Yasser, Mohamed, Elfar, Nehal, Shoueir, Kamel, El-Nabarawi, Mohamed, Helal, Doaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182695/
https://www.ncbi.nlm.nih.gov/pubmed/35679274
http://dx.doi.org/10.1371/journal.pone.0266019