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Interleukin-12 Plasmid DNA Delivery by N-[(2-Hydroxy-3-trimethylammonium)propyl]chitosan-Based Nanoparticles

Cationic polysaccharides are capable of forming polyplexes with nucleic acids and are considered promising polymeric gene carriers. The objective of this study was to evaluate the transfection efficiency and cytotoxicity of N-[(2-hydroxy-3-trimethylammonium)propyl] chitosan salt (HTCS), a quaternary...

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Detalles Bibliográficos
Autores principales: Dehshahri, Ali, Khalvati, Bahman, Taheri, Zahra, Safari, Farshad, Mohammadinejad, Reza, Heydari, Abolfazl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182864/
https://www.ncbi.nlm.nih.gov/pubmed/35683849
http://dx.doi.org/10.3390/polym14112176