11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway

We investigated the effect of an 11β-HSD1 inhibitor (H8) on hepatic steatosis and its mechanism of action. Although H8, a curcumin derivative, has been shown to alleviate insulin resistance, its effect on non-alcoholic fatty liver disease (NAFLD) remains unknown. Rats were fed a high-fat diet (HFD)...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Li, Jiali, Zhang, Meng, Yang, Wei, Qin, Wenqi, Zheng, Qinzhou, Chu, Yanhui, Wu, Yan, Wu, Dan, Yuan, Xiaohuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182913/
https://www.ncbi.nlm.nih.gov/pubmed/35684158
http://dx.doi.org/10.3390/nu14112358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182913/
https://www.ncbi.nlm.nih.gov/pubmed/35684158
http://dx.doi.org/10.3390/nu14112358

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