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11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway

We investigated the effect of an 11β-HSD1 inhibitor (H8) on hepatic steatosis and its mechanism of action. Although H8, a curcumin derivative, has been shown to alleviate insulin resistance, its effect on non-alcoholic fatty liver disease (NAFLD) remains unknown. Rats were fed a high-fat diet (HFD)...

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Detalles Bibliográficos
Autores principales:	Chen, Ying, Li, Jiali, Zhang, Meng, Yang, Wei, Qin, Wenqi, Zheng, Qinzhou, Chu, Yanhui, Wu, Yan, Wu, Dan, Yuan, Xiaohuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182913/ https://www.ncbi.nlm.nih.gov/pubmed/35684158 http://dx.doi.org/10.3390/nu14112358

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