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Construction and Evaluation of Chitosan-Based Nanoparticles for Oral Administration of Exenatide in Type 2 Diabetic Rats

Oral delivery of therapeutic peptides has been a daunting challenge due to poor transport across the tight junctions and susceptibility to enzymatic degradation in the gastrointestinal tract. Numerous advancement in nanomedicine has been made for the effective delivery of protein and peptide. Owing...

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Detalles Bibliográficos
Autores principales: Yang, Jian-Miao, Wu, Lin-Jie, Lin, Meng-Ting, Lu, Yi-Ying, Wang, Tian-Tian, Han, Min, Zhang, Bin, Xu, Dong-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9183037/
https://www.ncbi.nlm.nih.gov/pubmed/35683851
http://dx.doi.org/10.3390/polym14112181